World's Tallest Female Dog Is Nova, A Great Dane — Nova, a Great Dane, who's 2 feet, 11.51 inches tall is the world's tallest female dog, according to Guinness World Records. That's 35.51 inches from paw to shoulder for Nova, who takes up a lot of space in her owner's house in Addison, Ill. and there's 160 pounds packed onto that frame. She eats through 50 pounds per week. Owner Ann Suplee said strangers often say her dog looks like "a horse galloping" and ask her "Are you getting ready for the Kentucky Derby?" according to a statement from Guinness. But super Nova is a pipsqueak compared to Giant George of Tucson, the tallest male dog, who's 43 inches tall.